The Africa eCommerce Week: Empowering African Economies in the Digital Era was organised from 10 -14 December 2018 in Nairobi, Kenya by the United Nations Conference on Trade and Development (UNCTAD), the African Union, and the European Union, and hosted by the Government of Kenya. The outcome of the event is the Nairobi Manifesto on the Digital Economy and Inclusive Development in Africa which pinpoints a number of policy recommendations required for digital economy to bring inclusive and sustainable development to Africa and eschew wider inequalities and divides. The Manifesto further underlines how the engagement of all segments of society is significant for e-commerce to make a real and sustained contribution to development. To this aim, cross-cutting policy actions and new public -private partnerships are necessary alongside quality research and statistics to inform such policy actions.