The World Health Organization (WHO) and the International Development Innovation Alliance (IDIA) signed a strategic collaborative agreement to support the scale-up of health innovations. The two entities will work together to promote and facilitate the demand, supply, assessment, and scale-up of health innovations for the benefit of low and middle-income countries. The WHO can support its member states by helping to link impactful innovations to where they are most needed in countries, while the IDIA serves as a key collaborative platform for innovation funders worldwide. In their collaboration, the IDIA and the WHO will cover areas such as innovation demand, in which they will enhance needs identification that responds to national health priorities. The organisations also join forces to support the development of innovation and scaling knowledge and skills among WHO staff, member states, and development partners.